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OSBL8 rabbit pAb

OSBL8 rabbit pAb

ENT-A12521

Description

 

 

 

REF ENT-A12521
Category Antibody Polyclonal
Description OSBL8 rabbit pAb
Source Rabbit
Applications WB
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human OSBL8 AA range: 290-340
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 114882
Human Swiss Prot Nº Q9BZF1
Subcellular Location [Isoform 1]: Endoplasmic reticulum membrane ; Single-pass membrane protein . Nucleus membrane . The presence of the N-terminus extension contains an overall negative charge that may explain the weak localization to the cortical endoplasmic reticulum (Probable). .; [Isoform 3]: Endoplasmic reticulum membrane ; Single-pass membrane protein. Localizes to the cortical endoplasmic reticulum at the endoplasmic reticulum-plasma membrane contact sites. .

Other Name:

Background: This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],