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OPA1 rabbit pAb

OPA1 rabbit pAb

ENT-A11154

Description

 

 

 

REF ENT-A11154
Category Antibody Polyclonal
Description OPA1 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from part region of human protein
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 105kD
Human Gene ID 4976
Human Swiss Prot Nº O60313
Subcellular Location Mitochondrion inner membrane ; Single-pass membrane protein . Mitochondrion intermembrane space . Mitochondrion membrane . Detected at contact sites between endoplasmic reticulum and mitochondrion membranes. .

Other Name:

Background: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],