OCLN rabbit pAb
ENT-A11056
Description
| REF | ENT-A11056 |
|---|---|
| Category | Antibody Polyclonal |
| Description | OCLN rabbit pAb |
| Source | Rabbit |
| Applications | WB IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from part region of human protein. AA350-400 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 57kD |
| Human Gene ID | 100506658 |
| Human Swiss Prot Nº | Q16625 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . Cell junction, tight junction . |
Other Name:
Background: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],