OASL rabbit pAb
ENT-A8212
Description
| REF | ENT-A8212 |
|---|---|
| Category | Antibody Polyclonal |
| Description | OASL rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen | Synthesized peptide derived from human OASL. at AA range: 1-50 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 60kD |
| Human Gene ID | 8638 |
| Human Swiss Prot Nº | Q15646 |
| Subcellular Location | [Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm. |
Other Name: 2′-5′-oligoadenylate synthase-like protein (2′-5′-OAS-related protein) (2′-5′-OAS-RP) (59 kDa 2′-5′-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)
Background: caution:This may not be the true ortholog of mouse OASL.,function:Does not have 2′-5′-OAS activity, but binds double-stranded RNA and DNA.,induction:By interferons.,similarity:Belongs to the 2-5A synthetase family.,similarity:Contains 2 ubiquitin-like domains.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1.,tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.,