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O-FucT-2 rabbit pAb

O-FucT-2 rabbit pAb

ENT-A5334

Description

 

 

 

REF ENT-A5334
Category Antibody Polyclonal
Description O-FucT-2 rabbit pAb
Source Rabbit
Applications IHC;IF;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human POFUT2. AA range:361-410
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 23275
Human Swiss Prot Nº Q9Y2G5
Subcellular Location Endoplasmic reticulum . Golgi apparatus . Mainly located in the endoplasmic reticulum. .

Other Name: POFUT2; C21orf80; FUT13; KIAA0958; GDP-fucose protein O-fucosyltransferase 2; Peptide-O-fucosyltransferase 2; O-FucT-2

Background: Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008],