NUMB rabbit pAb
ENT-A4225
Description
| REF | ENT-A4225 |
|---|---|
| Category | Antibody Polyclonal |
| Description | NUMB rabbit pAb |
| Source | Rabbit |
| Applications | WB; IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000; IF/ICC 1:100-500;ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from the Internal region of human NUMB. |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 70kD |
| Human Gene ID | 8650 |
| Human Swiss Prot Nº | P49757 |
| Subcellular Location | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to perinuclear endosomes in an AAK1-dependent manner. . |
Other Name: NUMB; Protein numb homolog; h-Numb; Protein S171
Background: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],