NPC2 rabbit pAb
ENT-A12594
Description
| REF | ENT-A12594 |
|---|---|
| Category | Antibody Polyclonal |
| Description | NPC2 rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human NPC2 AA range: 9-59 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 10577 |
| Human Swiss Prot Nº | P61916 |
| Subcellular Location | Secreted . Endoplasmic reticulum . Lysosome . Interaction with cell-surface M6PR mediates endocytosis and targeting to lysosomes. . |
Other Name:
Background: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008],
