NM23A Rabbit rabbit pAb
ENT-A15964
Description
| REF | ENT-A15964 |
|---|---|
| Category | Antibody Polyclonal |
| Description | NM23A Rabbit rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | IHC 1:100-200 |
| Immunogen | Recombinant Protein of NM23A of NME1 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 17kD |
| Human Gene ID | 4830 |
| Human Swiss Prot Nº | P15531 |
| Subcellular Location | Cytoplasm . Nucleus . Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA. |
Other Name: NME1
Background: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of ‘A’ (encoded by this gene) and ‘B’ (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008],