NEK3 rabbit pAb
ENT-A10097
Description
| REF | ENT-A10097 |
|---|---|
| Category | Antibody Polyclonal |
| Description | NEK3 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Mouse |
| Reactivity | Mouse |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 55kD |
| Human Gene ID | 4752 |
| Human Swiss Prot Nº | P51956 |
| Subcellular Location | Cytoplasm . Cell projection, axon . |
Other Name:
Background: This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009],