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NCoA-5 rabbit pAb

NCoA-5 rabbit pAb

ENT-A6728

Description

 

 

 

REF ENT-A6728
Category Antibody Polyclonal
Description NCoA-5 rabbit pAb
Source Rabbit
Applications IHC;IF;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human NCOA5. AA range:345-394
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 65kD
Human Gene ID 57727
Human Swiss Prot Nº Q9HCD5
Subcellular Location Nucleus.

Other Name: NCOA5; KIAA1637; Nuclear receptor coactivator 5; NCoA-5; Coactivator independent of AF-2; CIA

Background: This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this gene have been described. However, the full length nature of one of the variants has not been determined. [provided by RefSeq, Jul 2008],