NBR1 Rabbit pAb
ENT-A1375
Description
| REF | ENT-A1375 |
|---|---|
| Category | Antibody Polyclonal |
| Description | NBR1 Rabbit pAb |
| Source | Rabbit |
| Applications | IHC |
| Reactivity | Human, Mouse, Rat |
| Reactivity | Human, Mouse, Rat |
| Dilution | IHC 1:100-200 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 120kDa |
| Human Gene ID | 4077 |
| Human Swiss Prot Nº | Q14596 |
| Subcellular Location | Cytoplasm, Cytoplasmic vesicle, Lysosome |
Other Name: 1A13B, MIG19, Nbr1
Background: NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.