N2DL1 rabbit pAb
ENT-A10321
Description
| REF | ENT-A10321 |
|---|---|
| Category | Antibody Polyclonal |
| Description | N2DL1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 26kD |
| Human Gene ID | 80329 |
| Human Swiss Prot Nº | Q9BZM6 |
| Subcellular Location | Cell membrane ; Lipid-anchor, GPI-anchor . Endoplasmic reticulum . In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi. . |
Other Name:
Background: The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],