MYPR rabbit pAb
ENT-A12668
Description
| REF | ENT-A12668 |
|---|---|
| Category | Antibody Polyclonal |
| Description | MYPR rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse;Rat |
| Reactivity | Human; Mouse;Rat |
| Dilution | WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human MYPR AA range: 206-256 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 5354 |
| Human Swiss Prot Nº | P60201 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . Myelin membrane . Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat. . |
Other Name:
Background: This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015],
