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MYPR rabbit pAb

MYPR rabbit pAb

ENT-A12668

Description

 

 

 

REF ENT-A12668
Category Antibody Polyclonal
Description MYPR rabbit pAb
Source Rabbit
Applications WB
Reactivity Human; Mouse;Rat
Reactivity Human; Mouse;Rat
Dilution WB 1:500-2000
Immunogen Synthesized peptide derived from human MYPR AA range: 206-256
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 5354
Human Swiss Prot Nº P60201
Subcellular Location Cell membrane ; Multi-pass membrane protein . Myelin membrane . Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat. .

Other Name:

Background: This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015],