Myp rabbit pAb
ENT-A3213
Description
| REF | ENT-A3213 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Myp rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARC. AA range:159-208 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 28kD |
| Human Gene ID | 8996 |
| Human Swiss Prot Nº | O60936-2 |
| Subcellular Location | [Isoform 1]: Nucleus, nucleolus . The SR-rich C-terminus mediates nuclear localization. .; [Isoform 3]: Cytoplasm .; [Isoform 2]: Cytoplasm . Mitochondrion . Sarcoplasmic reticulum . Membrane ; Lipid-anchor . Phosphorylation at Thr-149 results in translocation to mitochondria. Colocalized with mitochondria in response to oxidative stress. . |
Other Name: Myp; NOL3; Nop30; Nucleolar protein 3; apoptosis repressor ARC; apoptosis repressor with CARD; apoptosis repressor with caspase recruitment domain (CARD); muscle-enriched cytoplasmic protein; nucleolar protein of 30 kDa
Background: NOL3 encodes an anti-apoptotic protein nucleolar protein 3 that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for NOL3.