MYO15 rabbit pAb
ENT-A9152
Description
| REF | ENT-A9152 |
|---|---|
| Category | Antibody Polyclonal |
| Description | MYO15 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | IHC-p 1:50-300 |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 2990-3070 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 388kD |
| Human Gene ID | 51168 |
| Human Swiss Prot Nº | Q9UKN7 |
| Subcellular Location | Cell projection, stereocilium . Cytoplasm, cytoskeleton . Localizes to stereocilium tips in cochlear and vestibular hair cells. . |
Other Name:
Background: This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008],