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MTHFR rabbit pAb

MTHFR rabbit pAb

ENT-A3198

Description

 

 

 

REF ENT-A3198
Category Antibody Polyclonal
Description MTHFR rabbit pAb
Source Rabbit
Applications WB;ELISA;IHC
Reactivity Human;Mouse;Monkey
Reactivity Human;Mouse;Monkey
Dilution WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen The antiserum was produced against synthesized peptide derived from human MTHFR. AA range:314-363
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 75kD
Human Gene ID 4524
Human Swiss Prot Nº P42898
Subcellular Location cytosol,synapse,

Other Name: MTHFR; Methylenetetrahydrofolate reductase

Background: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009],