Msx-2 rabbit pAb
ENT-A6156
Description
| REF | ENT-A6156 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Msx-2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from the Internal region of human Msx-2. |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 28kD |
| Human Gene ID | 4488 |
| Human Swiss Prot Nº | P35548 |
| Subcellular Location | Nucleus. |
Other Name: MSX2; HOX8; Homeobox protein MSX-2; Homeobox protein Hox-8
Background: This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008],