MMP-10 rabbit pAb
ENT-A6134
Description
| REF | ENT-A6134 |
|---|---|
| Category | Antibody Polyclonal |
| Description | MMP-10 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000 Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MMP-10. AA range:361-410 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 54kD |
| Human Gene ID | 4319 |
| Human Swiss Prot Nº | P09238 |
| Subcellular Location | Secreted, extracellular space, extracellular matrix . |
Other Name: MMP10; STMY2; Stromelysin-2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2
Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],