Microcephalin rabbit pAb
ENT-A7299
Description
| REF | ENT-A7299 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Microcephalin rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MCPH1. AA range:91-140 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 93kD |
| Human Gene ID | 79648 |
| Human Swiss Prot Nº | Q8NEM0 |
| Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . |
Other Name: MCPH1; Microcephalin
Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010],