MEK3 Rabbit pAb
ENT-A1365
Description
| REF | ENT-A1365 |
|---|---|
| Category | Antibody Polyclonal |
| Description | MEK3 Rabbit pAb |
| Source | Rabbit |
| Applications | IHC |
| Reactivity | Human, Mouse, Rat |
| Reactivity | Human, Mouse, Rat |
| Dilution | IHC 1:100-200 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 34,39kDa |
| Human Gene ID | 5606 |
| Human Swiss Prot Nº | P46734 |
| Subcellular Location | Cytosol,Nucleus |
Other Name: MAP2K3; MKK3; PRKMK3; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK3; MAPK/ERK kinase 3
Background: Three alternatively spliced transcript variants of MEK3 encoding distinct isoforms have been reported. Isoform B utilizes a different start codon compared to isoform C resulting in the production of a N-terminal segment of isoform B which is shorter and distinct from isoform C . MEK3b is the predominant form of MEK3 and strongly activates p38 MAP kinase .