MDFI rabbit pAb
ENT-A3106
Description
| REF | ENT-A3106 |
|---|---|
| Category | Antibody Polyclonal |
| Description | MDFI rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MDFI. AA range:103-152 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 25kD |
| Human Gene ID | 4188 |
| Human Swiss Prot Nº | Q99750 |
| Subcellular Location | Nucleus . Cytoplasm . |
Other Name: MDFI; MyoD family inhibitor; Myogenic repressor I-mf
Background: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq, Jul 2008],