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MARH8 rabbit pAb

MARH8 rabbit pAb

ENT-A8924

Description

 

 

 

REF ENT-A8924
Category Antibody Polyclonal
Description MARH8 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from part region of human protein
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 32kD
Human Gene ID 220972
Human Swiss Prot Nº Q5T0T0
Subcellular Location Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein .

Other Name:

Background: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010],