LRP3 rabbit pAb
ENT-A6034
Description
| REF | ENT-A6034 |
|---|---|
| Category | Antibody Polyclonal |
| Description | LRP3 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LRP3. AA range:17-66 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 80kD |
| Human Gene ID | 4037 |
| Human Swiss Prot Nº | O75074 |
| Subcellular Location | Membrane ; Single-pass type I membrane protein . Membrane, coated pit . |
Other Name: LRP3; Low-density lipoprotein receptor-related protein 3; LRP-3; 105 kDa low-density lipoprotein receptor-related protein; hLRp105
Background: function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 4 LDL-receptor class A domains.,subunit:Binds GGA1 and GGA2.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.,