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KLF7 rabbit pAb

KLF7 rabbit pAb

ENT-A7516

Description

 

 

 

REF ENT-A7516
Category Antibody Polyclonal
Description KLF7 rabbit pAb
Source Rabbit
Applications WB;IHC
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution WB 1:500-2000;IHC-p 1:50-300
Immunogen The antiserum was produced against synthesized peptide derived from human KLF7. AA range:171-220
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 41kD
Human Gene ID 8609
Human Swiss Prot Nº O75840
Subcellular Location Nucleus .

Other Name: KLF7; UKLF; Krueppel-like factor 7; Ubiquitous krueppel-like factor

Background: The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],