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KDM4D rabbit pAb

KDM4D rabbit pAb

ENT-A9875

Description

 

 

 

REF ENT-A9875
Category Antibody Polyclonal
Description KDM4D rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from human protein . at AA range: 400-480
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 57kD
Human Gene ID 55693
Human Swiss Prot Nº Q6B0I6
Subcellular Location Nucleus .

Other Name:

Background: caution:It is uncertain whether Met-1 or Met-4 is the initiator.,cofactor:Binds 1 Fe(2+) ion per subunit.,function:Histone demethylase that specifically demethylates ‘Lys-9’ of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 ‘Lys-4’, H3 ‘Lys-27’, H3 ‘Lys-36’ nor H4 ‘Lys-20’. Demethylates both di- and trimethylated H3 ‘Lys-9’ residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,similarity:Belongs to the JHDM3 histone demethylase family.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,