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KCNE1 rabbit pAb

KCNE1 rabbit pAb

ENT-A9319

Description

 

 

 

REF ENT-A9319
Category Antibody Polyclonal
Description KCNE1 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse
Reactivity Human;Rat;Mouse
Dilution WB 1:500-2000 ELISA 1:5000-20000
Immunogen Synthesized peptide derived from human protein . at AA range: 40-120
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 14kD
Human Gene ID 3753
Human Swiss Prot Nº P15382
Subcellular Location Cell membrane ; Single-pass type I membrane protein . Apical cell membrane . Membrane raft . Colocalizes with KCNB1 at the plasma membrane (By similarity). Targets to the membrane raft when associated with KCNQ1 (PubMed:20533308). .

Other Name:

Background: potassium voltage-gated channel subfamily E regulatory subunit 1(KCNE1) Homo sapiens The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],