KChIP1 Rabbit pAb
ENT-A1329
Description
| REF | ENT-A1329 |
|---|---|
| Category | Antibody Polyclonal |
| Description | KChIP1 Rabbit pAb |
| Source | Rabbit |
| Applications | IHC |
| Reactivity | Human, Mouse |
| Reactivity | Human, Mouse |
| Dilution | IHC 1:100-200 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 30kDa |
| Human Gene ID | 30820 |
| Human Swiss Prot Nº | Q9NZI2 |
| Subcellular Location | Cell membrane, Cell projection, Cytoplasm, Membrane |
Other Name: KCNIP1,MGC9,MGC95,A type potassium channel modulatory protein 1
Background: Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels, GABAergic transmission and cell death.