JAML1 rabbit pAb
ENT-A10007
Description
| REF | ENT-A10007 |
|---|---|
| Category | Antibody Polyclonal |
| Description | JAML1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 43kD |
| Human Gene ID | 120425 |
| Human Swiss Prot Nº | Q86YT9 |
| Subcellular Location | Cell membrane ; Single-pass type I membrane protein . Cell junction . Localized at the plasma membrane and enriched in areas of cell-cell contacts (PubMed:12869515). |
Other Name:
Background: domain:The Ig-like V-type domain 2 mediates interaction with CXADR.,function:May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.,induction:Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,subcellular location:Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.,subunit:Interacts with CXADR.,tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.,