Jak3 (phospho-Tyr980/981) rabbit pAb
ENT-A13028
Description
| REF | ENT-A13028 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Jak3 (phospho-Tyr980/981) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen | Synthesized phosho peptide around human Jak3 (Tyr980 and 981) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 125kD |
| Human Gene ID | 3718 |
| Human Swiss Prot Nº | P52333 |
| Subcellular Location | Endomembrane system ; Peripheral membrane protein . Cytoplasm . |
Other Name: Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)
Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],