Jak1(phospho-Tyr1034/1035) rabbit pAb
ENT-A13030
Description
| REF | ENT-A13030 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Jak1(phospho-Tyr1034/1035) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen | Synthesized phosho peptide around human Jak1(Tyr1034 and 1035) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 132kD |
| Human Gene ID | 3716 |
| Human Swiss Prot Nº | P23458 |
| Subcellular Location | Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated. |
Other Name: Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
Background: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],