IRE1α rabbit pAb
ENT-A15893
Description
| REF | ENT-A15893 |
|---|---|
| Category | Antibody Polyclonal |
| Description | IRE1α rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | Purified recombinant fragment of human IRE1α (aa282-433) expressed in E. Coli. |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | |
| Observed Band KD | |
| Human Gene ID | 2081 |
| Human Swiss Prot Nº | O75460 |
| Subcellular Location | Endoplasmic reticulum membrane ; Single-pass type I membrane protein . |
Other Name: ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a
Background: The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008],