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Ihh rabbit pAb

Ihh rabbit pAb

ENT-A3965

Description

 

 

 

REF ENT-A3965
Category Antibody Polyclonal
Description Ihh rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human Ihh. AA range:209-258
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 45kD
Human Gene ID 3549
Human Swiss Prot Nº Q14623
Subcellular Location [Indian hedgehog protein N-product]: Cell membrane ; Lipid-anchor ; Extracellular side . The N-terminal peptide remains associated with the cell surface. .; [Indian hedgehog protein C-product]: Secreted, extracellular space . The C-terminal peptide diffuses from the cell. .; Cell membrane .

Other Name: IHH; Indian hedgehog protein; IHH; HHG-2

Background: This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015],