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HP-1α (5E3) Mouse mAb

HP-1α (5E3) Mouse mAb

ENT-A1615

Description

Ref ENT-A1615
Category Antibody Monoclonal
Alternative Name Antigen p25, CBX5, HEL25, Heterochromatin protein 1
Application WB, IHC
Source Mouse
Reactivity Human, Mouse, Rat
Dilution WB  1:500-1,000 IHC 1:100-200
Immunogen Recombinant Protein
Storage Stability PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality Monoclonal
Isotype IgG1
Concentration 1mg/mL
Observed Band(KD) 22kDa
Human Gene ID 23468
Human Swiss Prot No P45973
Subcellular Location Cytoplasm, Membrane, Nucleus

Background: Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure. All three HP1 family members (α, β, and γ) are primarily associated with centromeric heterochromatin.