HNF-4α (Acetyl Lys106) rabbit pAb
ENT-A8007
Description
| REF | ENT-A8007 |
|---|---|
| Category | Antibody Polyclonal |
| Description | HNF-4α (Acetyl Lys106) rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen | Synthetic Acetyl peptide from human protein at AA range: 106 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 55kD |
| Human Gene ID | 3172 |
| Human Swiss Prot Nº | P41235 |
| Subcellular Location | Nucleus. |
Other Name: Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)
Background: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],