HLAG rabbit pAb
ENT-A11082
Description
| REF | ENT-A11082 |
|---|---|
| Category | Antibody Polyclonal |
| Description | HLAG rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human |
| Reactivity | Human |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 37kD |
| Human Gene ID | 3135 |
| Human Swiss Prot Nº | P17693 |
| Subcellular Location | [Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane . Early endosome membrane .; [Soluble HLA class I histocompatibility antigen, alpha chain G]: Secreted .; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 4]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 5]: Secreted . Early endosome .; [Isoform 6]: Secreted .; [Isoform 7]: Secreted .; Cell projection, filopodium membrane . HLA-G trogocytosis from extravillous trophoblast’s filopodia occurs in the majority of decidual NK cells. . |
Other Name:
Background: HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008],