Histone H2A.X (Phospho Tyr142) rabbit pAb
ENT-A15933
Description
| REF | ENT-A15933 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Histone H2A.X (Phospho Tyr142) rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB: 1:1000-2000 |
| Immunogen | Synthetic Peptide of Histone H2A.X (Phospho Tyr142) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | |
| Observed Band KD | 15kD |
| Human Gene ID | 3014 |
| Human Swiss Prot Nº | P16104 |
| Subcellular Location | Nucleus . Chromosome . |
Other Name: H2AFX; H2AX; Histone H2A.x; H2a/x
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],