GGT2 rabbit pAb
ENT-A13251
Description
| REF | ENT-A13251 |
|---|---|
| Category | Antibody Polyclonal |
| Description | GGT2 rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human GGT2 AA range: 89-139 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 60kD |
| Human Gene ID | |
| Human Swiss Prot Nº | P36268 |
| Subcellular Location | Cytoplasm, perinuclear region . Endoplasmic reticulum . Co-localizes with calnexin in the endoplasmic reticulum. |
Other Name: Gamma-glutamyltranspeptidase 2 (GGT 2) (EC 2.3.2.2) (Gamma-glutamyltransferase 2) (Glutathione hydrolase 2) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase 2 heavy chain; Gamma-glutamyltranspeptidase 2 light chain]
Background: GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008],