GCS-β-2 rabbit pAb
ENT-A5661
Description
| REF | ENT-A5661 |
|---|---|
| Category | Antibody Polyclonal |
| Description | GCS-β-2 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 70kD |
| Human Gene ID | 2974 |
| Human Swiss Prot Nº | O75343 |
| Subcellular Location | Cytoplasm. |
Other Name: GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2
Background: Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.