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GBP1 rabbit pAb

GBP1 rabbit pAb

ENT-A5482

Description

 

 

 

REF ENT-A5482
Category Antibody Polyclonal
Description GBP1 rabbit pAb
Source Rabbit
Applications WB;IF;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human GBP1. AA range:71-120
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 68kD
Human Gene ID 2633
Human Swiss Prot Nº P32455
Subcellular Location Cytoplasm . Golgi apparatus membrane; Lipid-anchor ; Cytoplasmic side. Cell membrane . Secreted . Cytoplasmic vesicle . Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of IFNG induction. Golgi membrane localization requires isoprenylation and the presence of another IFNG-induced factor.

Other Name: GBP1; Interferon-induced guanylate-binding protein 1; GTP-binding protein 1; GBP-1; HuGBP-1; Guanine nucleotide-binding protein 1

Background: Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq, Jul 2008],