GABA A Receptor α2 rabbit pAb
ENT-A16006
Description
| REF | ENT-A16006 |
|---|---|
| Category | Antibody Polyclonal |
| Description | GABA A Receptor α2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | WB 1:1000-2000, IHC 1:100-200 |
| Immunogen | Synthetic Peptide of GABA A Receptor α2 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 51kD |
| Human Gene ID | 282236 |
| Human Swiss Prot Nº | P47869 |
| Subcellular Location | Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . Cell projection, dendrite . |
Other Name: Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2)
Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],