G2A rabbit pAb
ENT-A2777
Description
| REF | ENT-A2777 |
|---|---|
| Category | Antibody Polyclonal |
| Description | G2A rabbit pAb |
| Source | Rabbit |
| Applications | WB;IF;ELISA |
| Reactivity | Human;Mouse;Monkey |
| Reactivity | Human;Mouse;Monkey |
| Dilution | Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GPR132. AA range:293-342 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 42kD |
| Human Gene ID | 29933 |
| Human Swiss Prot Nº | Q9UNW8 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . Internalized and accumulated in endosomal compartments. LPC triggers the relocalization from the endosomal compartment to the cell surface (By similarity). . |
Other Name: GPR132; G2A; Probable G-protein coupled receptor 132; G2 accumulation protein
Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],