Frizzled-8 rabbit pAb
ENT-A7372
Description
| REF | ENT-A7372 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Frizzled-8 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FZD8. AA range:486-535 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 70kD |
| Human Gene ID | 8325 |
| Human Swiss Prot Nº | Q9H461 |
| Subcellular Location | Membrane; Multi-pass membrane protein. Golgi apparatus . Cell membrane ; Multi-pass membrane protein . Colocalizes with GOPC at the Golgi apparatus. . |
Other Name: FZD8; Frizzled-8; Fz-8; hFz8
Background: frizzled class receptor 8(FZD8) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008],