Fibronectin Mouse mAb
ENT-A1496
Description
| Ref | ENT-A1496 |
|---|---|
| Category | Antibody Monoclonal |
| Alternative Name | CIG, Cold insoluble globulin, fibronectin 1, FN, fN1, FNZ, GFND, GFND2, UgI-Y3 |
| Application | WB, IHC |
| Source | Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen | Synthetic Peptide |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Concentration | 1mg/mL |
| Observed Band(KD) | 285kDa |
| Human Gene ID | 2335 |
| Human Swiss Prot No | P02751 |
| Subcellular Location | Secreted, extracellular space, extracellular matrix |
Background: Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen.Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms.