Fhit rabbit pAb
ENT-A2739
Description
| REF | ENT-A2739 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Fhit rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FHIT. AA range:81-130 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 16kD |
| Human Gene ID | 2272 |
| Human Swiss Prot Nº | P49789 |
| Subcellular Location | Cytoplasm . Mitochondrion . Nucleus . |
Other Name: FHIT; Bis(5′-adenosyl)-triphosphatase; AP3A hydrolase; AP3Aase; Diadenosine 5′; 5”’-P1,P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein
Background: This gene, a member of the histidine triad gene family, encodes a diadenosine 5′,5”’-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009],