FH/Fumarase Rabbit pAb
ENT-A1151
Description
| REF | ENT-A1151 |
|---|---|
| Category | Antibody Polyclonal |
| Description | FH/Fumarase Rabbit pAb |
| Source | Rabbit |
| Applications | WB, IF |
| Reactivity | Human, Rat, Mouse |
| Reactivity | Human, Rat, Mouse |
| Dilution | WB 1:1,000 |
| Immunogen | Recombinant Protein |
| Storage Stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Observed Band KD | 50kDa |
| Human Gene ID | 2271 |
| Human Swiss Prot Nº | P07954 |
| Subcellular Location |
Other Name: Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1
Background: Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate in the mitochondria. Fumarase deficiency is caused by a mutation in the fumarase gene in humans. Fumarase deficiency is one of the few known deficiencies of the Krebs cycle or tricarboxylic acid cycle, the main enzymatic pathway of cellular aerobic respiration.