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FGF-12 rabbit pAb

FGF-12 rabbit pAb

ENT-A4085

Description

 

 

 

REF ENT-A4085
Category Antibody Polyclonal
Description FGF-12 rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from the Internal region of human FGF12. AA range:31-80
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 27kD
Human Gene ID 2257
Human Swiss Prot Nº P61328
Subcellular Location Nucleus .

Other Name: FGF12; FGF12B; FHF1; Fibroblast growth factor 12; FGF-12; Fibroblast growth factor homologous factor 1; FHF-1; Myocyte-activating factor

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],