FETUA rabbit pAb
ENT-A15866
Description
| REF | ENT-A15866 |
|---|---|
| Category | Antibody Polyclonal |
| Description | FETUA rabbit pAb |
| Source | Rabbit |
| Applications | WB; ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen | Synthesized peptide derived from human FETUA |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 197 |
| Human Swiss Prot Nº | P02765 |
| Subcellular Location | Secreted. |
Other Name: Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin;Ba-alpha-2-glycoprotein;Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B]
Background: function:Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.,polymorphism:There are two common alleles, AHSG*1 and AHSG*2. AHSG*1 has Thr-248/Thr-256; AHSG*2 has Met-248/Ser-256.,similarity:Belongs to the fetuin family.,similarity:Contains 2 cystatin domains.,subunit:Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond.,tissue specificity:Synthesized in liver and selectively concentrated in bone matrix. Secrete din plasma. It is also found in dentin in much higher quantities than other plasma proteins.,