FAN1 rabbit pAb
ENT-A13387
Description
| REF | ENT-A13387 |
|---|---|
| Category | Antibody Polyclonal |
| Description | FAN1 rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse |
| Reactivity | Human; Mouse |
| Dilution | WB 1：500-2000 |
| Immunogen | Synthesized peptide derived from human FAN1 AA range: 801-851 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 22909 |
| Human Swiss Prot Nº | Q9Y2M0 |
| Subcellular Location | Nucleus . Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2 (PubMed:20603015, PubMed:20603016). Localizes to stalled replication forks via its UBZ4-type zinc finger (PubMed:20935496). . |
Other Name:
Background: This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5′ flap endonuclease and 5′-3′ exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016],