FAM5C rabbit pAb
ENT-A13390
Description
| REF | ENT-A13390 |
|---|---|
| Category | Antibody Polyclonal |
| Description | FAM5C rabbit pAb |
| Source | Rabbit |
| Applications | WB |
| Reactivity | Human; Mouse;Rat |
| Reactivity | Human; Mouse;Rat |
| Dilution | WB 1:500-2000 |
| Immunogen | Synthesized peptide derived from human FAM5C AA range: 503-553 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 85kD |
| Human Gene ID | 339479 |
| Human Swiss Prot Nº | Q76B58 |
| Subcellular Location | Secreted . Mitochondrion . |
Other Name: Protein FAM5C (DBCCR1-like protein 1)
Background: This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],