ETL rabbit pAb
ENT-A6918
Description
| REF | ENT-A6918 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ETL rabbit pAb |
| Source | Rabbit |
| Applications | WB;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ELTD1. AA range:251-300 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 77kD |
| Human Gene ID | 64123 |
| Human Swiss Prot Nº | Q9HBW9 |
| Subcellular Location | Cell membrane ; Multi-pass membrane protein . |
Other Name: ELTD1; ETL; EGF; latrophilin and seven transmembrane domain-containing protein 1; EGF-TM7-latrophilin-related protein; ETL protein
Background: developmental stage:Up-regulated in the adult heart.,domain:The transmembrane domain is not required for cleavage, but it is required for dimer formation.,function:Could be involved in cardiac development.,PTM:Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 2 EGF-like domains.,subunit:Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Forms stable dimer at the cells surface.,tissue specificity:Mainly expressed in smooth muscle.,